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Protein Functionpathway Class Ras Growth o Src Growth o Abl Growth o APC Growth ts b-catenin Growth o Myc Growth o Bax Apoptosis ts Bcl-2 Apoptosis o hMLH1 Repair c hMSH2 Repair c ATM Repair c NBS Repair c BRCA1,2 Repair c p53 Controller ts pRb Controller ts Sginal role Many cancers Sarcomas Leukemias Colorectal cancers Colorectal cancers Many cancers Many cancers Trustd cancers Colon cancers Colon cancers Ataxia telangiectasia Nijmegen breakage syndrome Breastovarian cancers Most cancers Most cancers This page intentionally left blank 41 References 1.
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